Employment Barriers of Ex Offenders Essay

Finding Employment quickly is a priority for individuals leaving prison, and is usually mandated as a parole requirement. Ex offenders often require some flexibility in their jobs, in order to meet court ordered or parole mandates, such as drug counseling, and therapy, and to meet regularly with their parole officers. Returning prisoners also enter a competitive labor market with a combination of literacy problems, limited skills, and limited experience . Therefore they have limited access to job offering career ladders, mobility, training, or a job security. The lowest paying, lowest skilled jobs are the easiest to secure. Many make what they can of these opportunities because need to work to meet the obligations of their release. An ex offender is a person who has been convicted of criminal offense and has completed their sentence either in prison or in the community. Over 600,000 people are being released from prisons each year. Many suffer from various of serious difficulties as they attempt to reenter society. Among the most challenging situations they face is that of reentry in the labor market. Employment can be called a cornerstone of successful supervision. Employment for offenders reduces recidivism. It has been shown to be an important factor in reintegration, especially for men over the age of 27 years of age who characterize most individuals released from prison. Offenders reentering the community have a better chance if they are given enough support to stay out of trouble for the first 6 months following release. Offenders are destined for minimum wage, unskilled, menial jobs. Lack of education and job skills are the primary reasons, but the problem goes beyond that. Criminal convictions stigmatize offenders, directly limiting their future work opportunities and consequently encouraging them to return to crime for a source of income. Not only is it the predominant community attitude against knowingly hiring individuals with felony convictions, but strictly enforced laws prohibits licensing of such persons in many occupations. When you help offenders improve themselves and develop a sense of responsibility and self-esteem, employment opportunities will become more readily available A barrier is something that makes it more difficult for a person to job search or successfully complete the hiring process. Employment fills a vital need for most individuals; it provides income, social connection, and feelings, of societal contribution and self worth. For ex offenders returning to the community after a period of incarcerations, employment can make the difference between succeeding and returning to prison. (ISEEK) There are a numerous myths and truths with employing ex offenders: Myth: Ex offenders are only capable of doing manual or repetitive work Truth: Ex offenders represent a cross section of workforce. Many of them have valuable, in demand skills and qualifications Myth: Ex offenders are not educated  Truth: Nearly one in three have graduated from high school and or college Myth: Ex offenders are unreliable Truth: Ex offenders are as reliable as other workers. Myth: Once a criminal, always a criminal Truth: Ex offenders cannot prove themselves unless someone gives them a second chance Myth: Someone will always have to watch over an ex offender Truth: Ex offenders are people who paid the price for their crime and most of them want to make a fresh start. Ex offenders do not require extra supervision on the job Myth: Other employees will not want to work with them Truth: There is no need for employees other than line managers to know of the employee’s past Myth: The existence of a criminal conviction is an indication of being trustworthy Truth: Many people assume that ex offenders have basic character flaw that is not found in the normal population. Myth: Our company policy excludes ex offenders because of the type of work involved or legal restrictions. Truth: It is common misunderstanding those certain professions and certifications bar people with criminal records, just to name a few. Ex offenders have a variety of characteristics that greatly limits their employability and earnings which include limited education and cognitive skills, limited work experience, and substance abuse and other physical and mental health problems. Ex offenders face significant barriers to employment after release from prison. Barriers include employer attitudes towards individuals with criminal records, legal barriers, educational and financial obstacles, substance abuse and health issues, and lack of stable housing. The work experience that they had accumulated prior to incarceration was generally well below what it might have been in the absence of their participation in crime On top of that periods of time they have spent incarcerated have impeded them from gaining any additional private sector experience, an no doubt help erode whatever job skills, positive work habits or connections to employers they might have had beforehand. Thus, if and when they do attempt to reenter the labor market after incarceration, the poor skills and very limited work experience that they bring with them limits both employability and earnings potential. Most offenders reenter the outside world with little other than $ 40 of gate money or no money, no housing, no credit, no transportation, no driver’s license, no documents, no insurance, and no appropriate clothes for job interviewing and work settings. They also have limited access to health care services. Finding a job is difficult when you’re struggling to meet basic needs for food, shelter, and clothing. Many community based organization and support groups, such as Goodwill Industries, Salvation Army, churches and other nonprofit organization, assist offenders with such basic needs. Ron 2005) A large fraction of these men suffer from substance abuse and other health problems. Among the small fractions of ex offenders who are women, numbers suffer from depression and or past sexual abuse. All of these factors limits employability because they limit the basic job readiness that employers almost universally seek as a pre-condition for employment. Besides these skills a nd health problems, most ex offenders are minorities, nearly half are African American, an nearly a fifth are Latino and Asian. To the extent that minorities continue to suffer labor market discrimination, this will further impede the ability of ex offenders to gain employment or earn higher wages. Most return to low income and predominantly minority communities that have relatively few unskilled jobs, and to peer groups who presumably provide relatively a few contacts to the world of legitimate work. (H. J. Holzer 2003) In addition to the barriers these individuals face have little control, the attitudes and choices that they make may also limit their employment outcomes. After months and possibly years of incarceration, few ex offenders reenter society with a positive I can do it attitude. Many feel worthless, hopeless, and unwanted. Their negative attitudes are obvious to family members, friends, and employers. These attitudes affect their motivation to take action that lead to success in finding a job. They are filled with anxiety and uncertainty, uncertainty of how people will receive them, uncertain about their families, uncertain about their housing and financial situations, uncertain whether or not they will find a job, succeed on the outside or become another recidivism statistic. Ex offenders is a significant group in the labor market. It has been estimated that they constitute up to one third of the working population. At least 90 per cent of those leaving prison enter unemployment and they comprise between 2 and 3 percent of the average monthly in flow to the unemployment pool. Ex offenders re substantially more likely to remain unemployed in the long term rather taking a number of short term jobs. It is likely that a large number of these men might be able to find some kind of work if they search long enough, but at jobs that pay very low wages and provide few benefits or chances for upward mobility. Many ex offenders may simply choose to forego these employment options, in favor of illegal opportunities or more casual work. They may accept these jobs temporarily, but may not retain them for very long. Their attachments to the legitimate labor market might be quite tenuous over the longer term, both as a result of these relatively unappealing options, or perhaps because of their own estrangement over several years from the world of work. Thus, the limited employment outcomes that ex offenders experience will at least partly reflect barriers, perhaps compounded by their own attitudes towards and response to these circumstances. The barriers faced by ex offenders because of their very limited skills, poor health, and race or area of residence often reflect a difference between these characteristics and those sought by employers on the demand side of the labor market. Education is often a key to success. It frees offenders from many barriers to employment. Ex offenders tend to have low levels of education, lack many skills associated with better educated people. The poor skills and work experience of most offenders generally conflict with the skills and credentials sought by employers, even when trying to fill relative unskilled jobs. Those with substance abuse an other health problems are the least likely to be job ready, and will likely face few job offers or high discharge rates upon being hired. (Ron 2005) The federal government, as well as many state and local governments, place special legal restrictions on people with criminal records. Many drug offenders are prohibited from acquiring public housing or receiving other forms of public assistance. While employers cannot discriminate against individuals solely on the basis of their criminal record, they can refuse to hire if they can show that your background will negatively affect their workplace and business. State and local governments may include additional restrictions on certain opportunities, especially any position that deal with public safety. Finding work can be a challenge for some job seekers with criminal backgrounds. Having a criminal record can undermine employment prospects so that ex offenders are often penalized by the courts and later in the labor market. Having a job is widely recognized by ex offenders and those that work with them as the single most important factor in their resettlement and in preventing reoffending. It helps to know which barriers might be in the way and how to handle employer attitudes. Employers perform checks to gain additional information about ex offenders and checking seems to have no effect on hiring ex offenders for those employers not legally required to perform checks. Ex offenders looking for work often have a harder time than other job seekers. A felony conviction can be considered a barrier to employment. While employment is critical to ex offenders successful reintegration, prospective employers have their own set of interests when considering whether to hire an ex offender. Stoll,2008) Most employers are unaware of the tax incentives, bonding programs, and intermediary organizations currently in place to facilitate employment of returning offenders. Early work experience sometimes leads to wage growth over time, though this has not been particularly true among welfare recipients and others. Employers generally seem interested in the support system that seek to bridge the gap between ex offenders and prospective employers, but need to know more about the programs and how they fit with their needs. Although, many employers like to give a qualified es offender a second chance, they are averse to taking risks that they feel could threaten their workplace or reputation. In spite of the numerous barriers to employment of ex offenders, there is reason for some degree of optimism. Employers who had hired ex offenders reported mostly positive experiences. A great number of employers are reluctant to hire individuals with a past, citing lack of skills and work history, untrustworthiness, and fear of liability for negligent hiring, among other things. Criminal record information has the potential to present unintended barriers for offenders seeking employment. Across the country, states have provided employers with varying degrees of access to criminal record information on prospective and current employees. Advocates for limiting the availability of criminal record argue that providing such information to employers unfairly discriminates against ex offenders an makes it more difficult for them to obtain employment. Many employers argue that they should know who their employees are and whether they pose an unnecessary risk to the work place. (Holzer 2003) The United States Congress created two financial incentive programs to benefit employers who hire ex-offenders. One program gives an employer a tax break of $2,400 once an ex-offender has been hired and has worked for a certain number of hours. The other provides fidelity insurance bonds as an incentive to hire an ex-offender who might normally be considered high risk by mainstream insurance companies. These programs are often under-utilized. As a provider, you should educate your employer contacts about these programs and inform them that the State or your organization can assist them with the paperwork. Some employers have reported that they were â€Å"on the fence† about hiring an ex-offender, but the financial incentives â€Å"sealed the deal. † (Stoll 2008) Another program is The Federal Bonding Program issues fidelity bonds which serve as insurance policies for employers. Bonding protects an employer in case of theft, forgery, larceny, or embezzlement of money or property by an employee covered by the bond. The bond coverage is usually $5,000-$10,000, free for an employer, and good for up to one year. The bond becomes effective the first day of employment. Federal Bonding Program as an employer job-hire incentive that guaranteed the job honesty of at-risk job seekers. Job seekers who have in the past committed a fraudulent or dishonest act, or who have demonstrated other past behaviour casting doubt upon their credibility or honesty, very often are rejected for employment due to their personal backgrounds. Their past life experience presents an obstacle to their future ability to secure employment. More specifically, employers view these applicants as being â€Å"at-risk† and potentially untrustworthy workers. This fear is further heightened by the fact that Fidelity Bond insurance commercially purchased by employers to protect against employee dishonesty usually will not cover at-risk persons because they are designated by insurance companies as being not bondable. As a result, these job applicants are routinely denied employment. Carter 2007) Ex-offenders, including anyone with a record of arrest, conviction or imprisonment, and anyone who has ever been on probation or parole, are at-risk job applicants. When you combine figures for the US inmate population and the offender population in the free community who are now on probation or parole, the total number of persons under correctional supervision approaches 7 million individuals. More than 600,000 inmates are released from prison or jail annually. Past experiences reveal that 67% of them will be recidivists. Failure to become employed after release is a major factor contributing to the high rate of recidivism. Having a record of arrest, conviction or imprisonment functions as a significant barrier to employment since employers generally view ex-offenders as potentially untrustworthy workers and insurance companies usually designate ex-offenders as being not bondable for job honesty. (U. S. Department of Justice) There is restriction to the federal bonding program; workers must meet the State’s legal age for working. The job usually is to be for at least 30 hours per week. Workers must be paid wages with Federal Tax automatically deducted from their pay check. Self employed persons cannot be covered. A total of $5,000. 00 bond coverage is usually issued, with no deductible amount for the employer. The employer gets 100% insurance coverage. Larger bond amounts can be issued if the certified agency issuing the bonds has acquired a special bond package and has determined a larger bond amounts are appropriate.

Acct1101 Exam Final Sample

Venue____________________ Seat Number________ Student Number|__|__|__|__|__|__|__|__| Family Name_____________________ First Name_____________________ Venue____________________ Seat Number________ Student Number|__|__|__|__|__|__|__|__| Family Name_____________________ First Name_____________________ This exam paper must not be removed from the venue School of Business SAMPLE EXAMINATION ACCT1101 Account for Decis Making This paper is for St Lucia Campus students. For Examiner Use Only QuestionMark 1| | 2| | 3| | 4| | | | MCQ| | | | | | | | | | | | | | | | | | | | | | | | | | | | | |Total For Examiner Use Only QuestionMark 1| | 2| | 3| | 4| | | | MCQ| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Total Examination Duration:120 minutes Reading Time:10 minutes Exam Conditions: This is a Central Examination This is a Closed Book Examination – specified materials permitted During perusal – write only on the rough paper provided Materials Permitted In The Exam Ve nue: (No electronic aids are permitted e. g. laptops, phones) Any unmarked paper dictionary is permitted Calculators – Casio FX82 series or UQ approved (labelled) Materials to Be Supplied To Students: x 14 Page Answer Booklet Rough Paper 1 x Multiple Choice Answer Sheet Instructions to Students: * Answer all questions using the writing book and the Multiple Choice Answer * Sheet provided. * This sample exam is intended to be an indication of the content of the main and final exams. It is not intended to be a complete indication of the content of the supplementary exam, as this exam also assesses all course content Question 1 Go Stop Limited is preparing its budget for the quarter beginning 1 January 2013. The bank balance at 1 January is expected to be $10,000,000.The directors have a policy to purchase just enough to cover that month’s expected sales. Purchases are to be paid for by the end of the following month. Sales are on credit as follows: Receipts:| | Current m onth| 60%| month before| 30%| 2 months before| 10%| Total| 100%| | | Budgeted Sales are: $,000| $,000| $,000| $,000| $,000| November| December| January| February| March| 46,800 | 48,000 | 50,000 | 52,000 | 56,000 | The firm’s gross profit margin is 30%. The following fixed monthly expenses are all paid on cash terms ($, 000): Wages| 15,000| Rent| 6,000| Rates| 3,000| Insurance| 1,500|An expensive piece of equipment was paid for in February, costing $1,200,000 Required: 1) Prepare the company’s cash budget for the three months beginning 1 January showing the balance at the end of each month. Show workings. Use the proforma cash budget sheet that follows 2) Advise the management on the forecast cash position 3) Advise management of the importance of Cash Management Answer Sheet: Go Stop Limited | January| February| March| Total| | $,000| $,000| $,000| $,000| Receipts:| Â  | Â  | Â  | Â  | | Â  | Â  | Â  | Â  | Total Cash receipts| | | | | | | | | | Payments:| | | | |DO NOT WRITE ON THIS PROFORMA IN THE EXAM:USE AS A GUIDE ONLY AND WRITE YOUR ANSWER IN THE NORMAL GREEN ANSWER BOOKLET| | | | | | | | | | | | | | | | Total cash payments| | | | | | | | | | Net cash flows| | | | | | | | | | Opening Bank Balance| | | | | Closing Bank Balance| | | | | Question 2 Given below is a table that sets out the annual budgeted income statement for a large clothing retailer, together with actual performance figures. The retailer has several stores located all over Australia and New Zealand. Sales are made directly over the counter and also by mail delivery Income statement| for year ended 30 June| Budgeted $,000| Actual $,000| | | | Sales| 4,200,000| 5,000,000| Cost of sales| 3,640,000| 3,430,000| Marketing| 12,000| 40,000| Distribution costs| 10,000| 23,000| Administration costs| 213,000| 316,000| Interest expense| 104,000| 110,000| Abnormal expense| 0| 25,000| Net profit| 221,000| 1,056,000| Required: i. Calculate the variances for each item and state whet her they are Favourable (FAV) or Adverse (ADV) ii. Comment on each variance in light of the information given about the company and suggest further investigation that will be necessary to better ascertain the cause of these variances iii.Comment on the company’s overall performance during the year and discuss the key areas that the business should be considering Question 3 James Wilson, process engineer, had been given the task of redesigning an existing process to improve environmental performance. He knew that the acceptance of a more environmentally efficient process would depend on its economic feasibility. The process design required new equipment and an infusion of working capital. The equipment would cost $450,000 and its cash operating expenses would total $90,000 per year.The equipment would last for seven years but would need a major overhaul costing $45,000 at the end of the fifth year. At the end of 7 years, the equipment could be sold for $30,000. The annual depr eciation for this equipment using the straight line method would be $60,000. An increase in working capital (Current Assets – Current Liabilities) totalling $45,000 would also be required at the beginning. This would be recovered at the end of seven years. On the benefit side, James estimated that the new process would save $202,500 per year in environmental costs by eliminating fines and clean-up costs.The cost of capital is 10%. Required: 1. Prepare a schedule of relevant net cash flows for the proposed project. 2. Calculate the NPV of the project. 3. Should the new process design be accepted? 4. What factors should James consider other than environmental ones when deciding whether to go ahead with this project? Question 4 Sailaway Limited is a small yacht builder. It has operated successfully for many years from a factory that allows for production of 40 yachts per year. In most years the company can sell all the yachts it can produce. The selling price of each yacht is $1 2 600.Variable labour and materials costs are $7 750 per yacht, and the fixed costs associated with running the business from the present factory are $58 200. The company's directors are meeting to discuss a proposal to increase the business's production capacity. A neighbouring factory has become vacant and it would be possible to rent the additional space in order to produce more yachts. The additional capacity in terms of production would be 20 yachts. The sales director is confident that, with the growth in the leisure yachting market, he will be able to sell the additional yachts.Variable costs per yacht will remain the same because the same labour and materials are used. However, the expansion would produce an additional $14 550 in fixed costs. Required: 1. Advise the company’s directors on whether to go ahead with this proposal 2. What would be the break even in number of yachts: a. Without the proposal b. With the proposal 3. What is the margin of safety in number of yachts and percentage of yachts c. Without the proposal d. With the proposal From this comment of which is the riskiest alternative Multiple choice questions:Answer these questions on the separate multiple choice answer sheet Each question carries one mark 1. One of the approaches to setting budgets is known as the ‘top down' approach. This is best described as: A| production budget set first and working from this to other budgets. | B| setting the sales forecast and working from this to other budgets. | C| budget targets set by senior management. | D| budget targets set at the lowest level of management. | 2. High operating gearing refers to: A| an activity with relatively high variable costs compared with its fixed costs. B| an activity with relatively high fixed costs compared with its variable costs. | C| an activity with relatively low fixed costs compared with its variable costs. | D| an activity with fixed costs equal to its variable costs. | 3. The decision rule for th e accounting rate of return method of assessing investment projects is to accept all projects with: A| a positive return. | B| the highest return subject to a minimum required return. | C| the highest return. | D| none of the above. | 4. A disadvantage associated with the use of the accounting rate of return method for assessing investment opportunities is:A| it is a method that is not widely understood by business. | B| it is based on an accrual approach rather than cash flows. | C| it ignores the time value of money. | D| B and C. | 5. The time value of money is an important concept in investment decisions as it takes into account that: A| a dollar received tomorrow is more valuable than a dollar received today. | B| a dollar received today is equal to a dollar received tomorrow. | C| it takes time to earn profits. | D| a dollar received today is more valuable than a dollar received tomorrow. | END OF EXAMINATION

Biomedical and Biopsychosocial Models of Healthcare

Biomedical and Biopsychosocial Models of Healthcare Critical Evaluation on the Future of Healthcare: The Biomedical or the Biopsychosocial Model The Biomedical Model This model has been in existence since the mid-19 th century and was predominant for physicians in the diagnosis of diseases. It comprises of four elements. It argues that, that health constitutes the freedom of pain, disease or defect which implies the normal human is healthy. In this model, the focus on the physical processes such as biochemistry, physiology and pathology of a disease do not take into consideration the role played by individual subjectivity or social factors. Unlike the biopsychosocial model, the biomedical model fails to consider negotiation between a doctor and patient in determining diagnosis. The main focus in this model is purely biological factors. It excludes social influences, environment and the psychological ones. Western countries have adopted it as a leading modern way for which health professionals treat and diagnose conditions. Regardles s of the limitations that this model expresses, it has been critical in the development of programs to control infectious diseases. In addition, it feeds more information to the biopsychosocial approach (White, 2009). The Biopsychosocial Model This is an approach that states that psychological, social and biological factors all play a key role in the human functioning in relation to illness and disease. Health is thus understood by concentrating on biological, social and psychological factors rather than entirely focusing on biological terms. It contrasts to biomedical model. Biomedical model takes the position that every disease process can be explained in accordance to deviations in normal functions such as injury, developmental abnormality in genes or virus (White, 2009). This model is used in the fields of medicine, health sociology and psychology and nursing. The acceptance, novelty and prevalence of the biopsychosocial model demonstrates variation across cultures. The model ha s been developing over time and will only mature further with health psychology designs and research. The Future of Healthcare The biopsychosocial model is at the heart of the future of healthcare. Specialization in healthcare has advanced to fields of health psychology, psychiatry, chiropractic, clinical psychology, family therapy and clinical social work. Majority of clinicians will engage the elements of biopsychosocial and biomedical models in the practices they engage in. However, it is arguable that all illnesses whether functional or organic can be managed best going by the biopsychosocial framework rather than the biomedical in practice. The two models seem to share the same goal which is improving the improvement of the patient’s well-being. What differs is the scope on which the physician considers impairment including its origin and the possible remedies. The biopsychosocial framework expands the meaning of this goal and applies it in clinical processes. Illness is approached as the subjective sense of suffering by the patient. The goal of managing the disease thus needs to identify the specific exposures of the patient which are biological, social and psychological. Potential Disabilities of the Biomedical Model The biomedical model will lose its position in the future of healthcare as it assumes that social and psychological processes are irrelevant to the disease’s process. The potential disabilities it exposes are massive. It mainly has three liabilities. First, the model is reductionist in nature. It reduces illness to lower level processes. These include chemical imbalances and disordered cells. It thus fails to recognize the general role of psychological and social determinants. Secondly, the model is a single-factor model. The explanation for illness is in terms of biological malfunctions rather that recognition of a variety of factors with only a few being biological in the causation of illness. The third liability is that the model assumes a mind-body dualism. It maintains that the body and mind are two separate entities. The final but not least liability is that the model puts more emphasis on illness over health. The focus is aberrations that cause illness instead of the conditions that would promote health.

Summary of The Changing Demographics of America Essay

Summary of The Changing Demographics of America - Essay Example According to Kotkin this is as opposed to other developed countries such as Japan; South Korea, Europe and China whose population is estimated to decrease. The high young population is attributed by the high fertility and immigration rates. Most of the European countries are estimated to be authentic old-age homes as a high percentage of their populations will be 65 years and above (Kotkin, 2010). According to Kotkin, the high immigration rates and the high fertility rates of US have prompted some critics by environmentalists who are worried by additional 100 million people in the country by 2050. They are calling for national policies to control the high immigration and fertility rate. Colleen Heenam, an author and one of the environmental activists articulates that Americans who favour huge families don’t take responsibility for their prejudicial actions towards population growth which will lead to shortage of the limited resources. Peter Kareiva, a scientist had suggested that the best way to reduce carbon emissions is to give birth to no child (Kotkin, 2010). These critiques forgot to put into consideration that paucity of young people and low population in the country will pose a threat to the country’s labour productivity and be a scourge to the nation’s eudemonia (Kotkin,

Discuss how continuity and progression can be promoted in physical Essay

Discuss how continuity and progression can be promoted in physical education in the transition from Key Stage 2 to Key Stage 3 and in teaching and learning acro - Essay Example Continued school developmental work on transition from KS2 to KS3 is improving continuity and progression in physical education between the key stages in a number of areas of activity. Physical education provides a valuable involvement to the whole school curriculum. Students are engaged in developing their knowledge, skills and awareness within a range of physical activities so that they can perform with growing competence and poise. PE provides the chance for students to be innovative, competitive and work cooperatively together, i.e. to know-how to work as a team, in a variety of contextual situations. The diverse learning exposures within physical education tend to encourage spiritual, social, cultural and moral developments with personal growth in terms of self-confidence and self-esteem. The whole PE experience provides cerebral and physical challenges which promote positive approach to learning [3]. Physical education teaches students the importance of exercise and its role to maintaining a consistent healthy lifestyle. It exploits a range of psycho-motoring skills and develops stamina and strength. Students transferring from KS2 to KS3 get to build and maintain physical prowess, as well as to increase their mobility and flexibility. They develop the capacity to express their ideas freely and build upon the ability to be able to produce skilful and creative solutions to problems. PE allows the cultivation of personal qualities of commitment, passion and fairness. It enables the development to appreciate physical concepts of fair play, honest friendly competition and build-up on good character. They build upon the ability to appreciate the artistic qualities of physical movement. PE teaches the students to develop confidence by understanding the capabilities and limitations of oneself and others. Students are further taught to respect and obey logical instructions, regulations a nd able to always put these into

Students interest in a career as a civil engineer for the Kentucky Essay

Students interest in a career as a civil engineer for the Kentucky Transportation Cabinet - Essay Example The skills acquired are relevant to the Kentucky Transportation Cabinet since they deal with projects that rely on vast knowledge in physical sciences and mathematics. I am a female, and have obtained an ACI Certification. I feel I have what it takes to become a member of the Kentucky Transportation Cabinet. However, my certificate will be expiring after five years, meaning that I will be able to offer quality and certified services for the next five years. I am open-minded, and like learning new skills. I am committed in playing an important role in key debates that pertains sustainability, climate change as well as energy efficiency. While I was studying, I often attended seminars and workshops, as well as attachments with leading organizations, which enabled me to solve work related problems. Thus, I understand that civil engineering works need attention and teamwork. While studying mathematics in school, I enjoyed problem solving, which is another desired quality for civil engineers. I am now looking for an opportunity to advance my career, and I am quite sure that Kentucky Transportation Cabinet has all what I

Charles Chesnutt Debates Washington and Du Bois Essay

Charles Chesnutt Debates Washington and Du Bois - Essay Example Washington: Of course laws are manipulated to hinder our progress and advancement. But we as blacks, in our own hunger and impatience also endeavor to regulate and manipulate perhaps too much and all at once. Nonetheless, in this social tug of war, we have already managed to strive and attain a compromise with the powers that be. Du Bois: A compromise is not enough. As Chestnutt says, the persistent funk of the matter still exists. This idea about obstructions and obstacles has already been established and understood in all of humanity; it is an absolute truth of all struggles, as in the Greek and Roman tragedies. Obstacles caused by the enemy as well as by the protagonist are inevitable in all epics and in all realities. Such 'evil' powers have always existed to obstruct the advancement of any race, of any people C: Now, beyond fairytales and myths, if we are truly emancipated should not all of society take up the responsibility of our emancipation Should not all of society, black or white, be held accountable for such manipulations of power that continue to degrade and oppress our progress W: Such responsibility and accountability take time. We as blacks have to accommodate ourselves to our newly acquired rights and we need to pacify the fears of the whites to establish a dialogue and a trust. D: Just as much as the whites have to accommodate to us ... Obstacles caused by the enemy as well as by the protagonist are inevitable in all epics and in all realities. Such 'evil' powers have always existed to obstruct the advancement of any race, of any people C: Now, beyond fairytales and myths, if we are truly emancipated should not all of society take up the responsibility of our emancipation Should not all of society, black or white, be held accountable for such manipulations of power that continue to degrade and oppress our progress W: Such responsibility and accountability take time. We as blacks have to accommodate ourselves to our newly acquired rights and we need to pacify the fears of the whites to establish a dialogue and a trust. D: Just as much as the whites have to accommodate to us being free, to us being educated, respected and held among the great intellectuals of society. We cannot humble ourselves too much or we'll be slaves again, brother. W: Yes but absolute emancipation will never happen over night. You cannot merely change white to black by adding in a completely new color which has never existed. The desired shades of grey or any color for that matter must go through their process to reach a compromise. C: Maybe you're right. We don't want white or black, we want white and black, and that is what black folks and white folks do not understand. The war is over. Perhaps it's time for an understanding- D: Well, I think what there needs to be is a sincerely desired resolution by both parties. The blacks need to establish themselves wholeheartedly and maybe even a little forcefully with their God given rights- W: Yet sensibly- D: To an extent. Whereas the whites need to earnestly acknowledge that yes, there must indeed be an acceptance of our rights and not a fear. One cannot try to outsmart

People mangment Essay Example | Topics and Well Written Essays - 2500 words

People mangment - Essay Example As such, contemporary organisations have provided the arena wherein growth and success of the firm is tied up with the growth and participation of the employees for the success of the organization (Li, Guohui & Eppler 2008; Wolfgang & Brewster, 2005). However, it is not only contemporary organizations that have undergone changes. The nature of the contemporary workforce has also been modified (Jinzhao, 2007). Globalization is not only about removal of economic barriers among nations and movements of capital, investments and goods, but it also pertains to the more free movement of people across nations reducing the significance of physical borders as barriers (Fischer, 2003; Suarez-Orozco & Qin-Hilliard, 2004). In this regard, the nature of the contemporary workforce has been revolutionized from a homogenous workforce to a heterogeneous, diverse workforce (Maxwell, McDougal & Blair, 2001). The idea of a heterogeneous work force means â€Å"differences in attitudes, and behaviors of e mployees relative to gender, race, age, ethnicity, physical ability, and other relevant characteristics† (Jinzhao, 2007, p. 60). ... This reality pervades all organizations regardless of their nature. In the light of this change in the nature of the contemporary workforce, the concepts of diversity and equality will be discussed vis-a-vis the reality of women in the workplace. As such, this research will address the following questions: what are diversity and equality policies? Do they work? Finally, do they open possibilities and opportunities for women? DIVERSITY AND EQUALITY POLICIES: A CONCEPTUAL LOOK Diversity in the workforce is initially perceived as a response toward the increasing diversity of the consumers in the market (Agocs & Burr, 1996). From there, it has been observed that capitalizing on existing differences among the employees provides benefits to the organization. Diversity in the workforce fosters and encourages creativity, innovativeness, diverse views and approaches to a particular problem, opens alternative perspectives and taps diverse talents from varying backgrounds to harness the organiz ations problem-solving and decision-making skills. For these reasons, scholars are in agreement that managing diversity is a challenge organizations must be willing to undertake because using the pot of diversity opens creativity and innovativeness for the organization (Agocs & Burr, 1996; Jinzhao, 2007; Bartz et al,1990; Maxwell et al, 2001). Moreover, it has been claimed that diversity should not be limited only to the physical and observable differences existing among employees. Intangible differences such as background, values, religious orientation, beliefs and the like are as important as physical and tangible differences like age, sex, disabilities, color of the skin, accent of speech and other similar qualities, since, if all these differences are harness,

Advertising Consultation Case Study Example | Topics and Well Written Essays - 2000 words

Advertising Consultation - Case Study Example This paper discusses an advertising consultation of Ben Cohen and Jerry Greenfield, one of the leading producers of ice cream products in the UK market and other parts of the country. The company history date back in 1981 when two friends, Ben Cohen and Jerry Greenfield took a correspondence ice cream course after their college education. They their first ice cream shop in a renovated petrol filling station in Burlington, Vermont and later on their first plant in 1981. Since then, they have expanded their ice cream market to France, Canada, Belgium and Netherlands. Lately, there has been a great threat in the ice cream industry more so from Haagen-Dazs, a leading ice cream company that has a the highest market share in the market. This paper discusses advertising consultation advices to Ben Cohen and Jerry Greenfield on the tactic they should apply for them to survive in the market. To maximise sales within any market a sound, well defined target market group of consumers is essentia l. Describe/identify the UK target market that would best suit Ben and Jerry's premium ice cream. Is its primary segment different from that of Haagen-Dazs target Are the two brands too similar in their positioning to the consumer.Ben and Jerry's premium ice cream can still dominate the market thereby maximising sales within any market.... (Steenkamp and Ter Hofstede, 2002) Ben Cohen and Jerry Greenfield need to be market-focused or customer-focused in for them to succeed in the ice cream industry. They should first determine their potential customer's desire and then produce super premium ice cream appropriately according to the taste and preferences of their target group. According to marketing theory and practice, it is usually justified on the belief that a customer uses a product because they have a need or because they have perceived benefits. (Pine, 1993) Before Ben and Jerry Greenfield can market their premium ice cream, they need to strategize their target. This call upon them to use targeting strategy which is the selection of the customer they wish to sell to them their premium ice cream. For this case, their decision on targeting strategy should call upon them to ask themselves which segment they need to target. When Ben and Jerry Greenfield will be targeting, they should follow the following steps: Market segmentation Target choice and Product positioning 1 Market segmentation is usually the process whereby a market is divided into distinct subsets that have similar needs or those that behave in the same way. Since each segment is fairly homogeneous in their needs and attitudes, they are likely to respond similarly to a given marketing strategy. This means that they are likely to have similar feeling and ideas about a marketing mix comprised of a given product that is sold at a given price, promoted and distributed in a certain way. (Steenkamp and Ter Hofstede, 2002) Usually, the process of segmentation is distinct from targeting and positioning as targeting chooses which segments to address while positioning designs an appropriate marketing mix for each segment. For

Differences between the old version of the international commercial Essay

Differences between the old version of the international commercial terms (2000)and the new ones (2011) - Essay Example Defining the changes which have been made between the different years and associating this with the terms regulated by the ICC, or international chamber of commerce organization, can also redefine what is now expected when working with trade agreements across nations. The current changes which are being initiated are based on redefining the terms of trade, specifically to open different regions while protecting businesses that are associated in different regions of the world. The purpose of this research paper will be to redefine the amount of supply and demand between regions while creating a different set of terms and agreements with the new international commercial terms. It has been noted that a large variety of changes have been made between the year 2000 and 2011. These are being redefined to open the trade of import and export and to protect businesses with arbitration and mediation. More important, these are changing the way in which different businesses associate with legalities, arbitration and mediation in various countries. By examining the redefinition of terms, the paper will be able to redefine what the terms may lead to as well as how this is changing the outlooks that are associated with business imports and exports among various countries. Import and export terms have been growing since the beginning of the Industrial Revolution, specifically because both quality and quantity can be maintained through basic manufacturing agreements. To ensure that the export and import terms are met and qualified, legalities and representation of both sellers and buyers have also been noted. The first representation was in 1936 with the development of the International Chamber of Commerce, or ICC. The main objective of the ICC was to regulate trade and to ensure that there were fair agreements which were made across national borders. The development of the ICC led to the Inco terms, which were rules and agreements which

National Association for Stock Car Auto Racing Essay Example for Free

National Association for Stock Car Auto Racing Essay The case analyses the dynamics of high performance teams using the example of Jeff Gordon’s racing team, a member of National Association for Stock Car Auto Racing (NASCAR). Jeff Gordon was often described as a racing sensation, winning 40 individual races in a four year period. While Gordon was a star and a brand, few spectators knew that his outstanding performance should have been to a large extent attributed to his team consisting of more than a hundred of committed individuals, Rainbow Warriors pit crew, and supervised by visionary team leader, Ray Evernham. According to expert opinion, there are three key ingredients that provide for success in car racing, namely people, equipment and money. While cars and equipment are made approximately even in performance in order to make racing more competitive and spectacular, it is up to pilot and his crew to gain an advantage over the opponents. Effectiveness of Rainbow Warriors pit crew gave Gordon on average a one-second advantage with each pit stop. Ray Evernham managed to gather and develop such an outstanding crew by applying several important principles of group work management. He fostered group cohesion by a variety of methods and believed that sound preparation, ego less teamwork, and original strategizing are the inherent components of success in car racing. In his view, the emphasis should have been on team performance rather than individual performance. In case of a victory, prize money were distributed among all members of the crew; more importantly, the money earned by Evernham through speaking tours and autograph signings were also shared. In 1999, Ray Evernham resigned to start his own organization. Brian Whitesell took over as the crew leader on an interim basis; despite his academic qualifications, he was unable to lead the crew in the way Ray Evernham was. Robbie Loomis became the permanent crew chief, and during six months of the turbulent transition period Gordon haven’t won a single race. However, Loomis was able to deliver a strategic turnaround and ensure Gordon’s continuous success. Answers to Review Questions As concerns the philosophy behind high performance teams, Ray Evernham’s three principles (preparation, ego less teamwork, and innovations in strategizing) are universally applicable in any organization. Evernham was successful in implementing these principles in practice by encouraging teamwork, recognizing that ‘team IQ’ was greater than IQ of any individual member, and promoting cohesion through such practices as a ‘circle of strength’ when all team members sit in a circle facing each other as a symbol of their collective strength. People, management, and psychology came together under his leadership to ensure superiority over the opponents’ performance. The emphasis on continuous learning made it possible to stay ahead for many seasons in a row. However, Evernham also warned against excessive perfectionism that might have been unproductive. Honest acknowledgement of strength and weaknesses and strive for improvement were sufficient to secure a place on top. This is interrelated to yet another principle used by Evernham, namely keeping the egos in check and not boasting any technical or strategic privileges in front of the opponents. The time when a successful leader is replaced by somebody else is a test of group’s cohesiveness and commitment. The downside of the transition period is reduced efficiency and increased entropy. However, the advantage is associated with the fact that such a situation allows the team to reinvent itself to become even stronger and more cohesive, especially if a transformational leader arrives to manage the team. Summary for Managers There are several important implications for managers that stem from the analysis of this case. First of all, the principles which are applied to boost team performance are more or less universal. Focus on teamwork and organizational learning is crucial. The case study clearly states that high performance teams do not emerge by themselves – they require an effective recruiting strategy and attention to learning every detail of the work process. Attributing success and failure to the entire group rather than individual members has proven to increase the group’s performance and motivation. The second important implication has to do with group cohesiveness. When skills and knowledge of all group members combine in a way that exceeds the sum of knowledge of all individual members, the synergy effect can be observed, i. e. the system as a whole has certain qualities its elements do not have. Therefore, it is of paramount importance to pay attentive to group cohesion so that exceptional results can be achieved with limited human resources available in each organization. The third implication concerns team performance in the times of change. The case clearly demonstrates that both leadership and teamwork are equally important for success. With no strong leadership, Gordon’s team was not able to deliver outstanding results. However, the speed at which it was able to regain its position suggests that there were certain qualities of a team that made it possible to succeed even after a change of leadership style. A cohesive team can function efficiently under any talented leader due to close ties between team members and unique group culture that promotes continuous learning and shared responsibility.

Lan Base Entrance Examination System Essay Example for Free

Lan Base Entrance Examination System Essay Long b books were known, the storyteller of many lands including our own, told tales in order to entertain their listeners, as well as, to convey the moral lessons which these stories usually impart. In the course of time, these stories were handed down from generation to generation and worn smooth by ages of telling and retelling. Stories were generally tailored to reply information, become outlet for political and/ or social criticism, and sometimes simply entertain. Many storyteller acquired that distinctive style and unique from which among them well-loved and highly appreciated qualities. But as time passed by, the use of traditional multimedia such as slides, videos, filmstrips, audio recording and overhead projectors paved way in upgrading the storytelling techniques to help readers understand more clearly what the authors want to convey. The use of these traditional multimedia opened doors for new discoveries, discoveries that he will help the students enhanced their learning capabilities through the teaching- learning processed. Thus, with the method of teaching to be effective must be supplemented by other methods or devices that will increase and enhanced quality instruction. But time changes the trends in every generation.† The key to this revolutionary advancement is, of course, the computer. A combination of electronic memory with programs that tell the machine how to process the stored data, computers were still a scientific curiosity in early 1950’s Computer, as a tool and as a part of teaching and learning process, has been a major breakthrough in the educational system. In our modern way situation, a lot of stories are being relayed to students especially those in the elementary level in forms of movies, books and newspapers. What seems notable was that although most movies featured†hitech† technological advancements, many lack a very important aspect of the story telling, the imparting lesson. As a consequence, children member a movie or story based on what they saw or heard but not the lesson of the story, which is the more important aspect of storytelling. Worst, most tabloids being sold, which openly contain pornographic pictures and erotic stories, are within the reach of these kids. The researchers believe that one way minimizing, if not eliminating this situation, was creating by interactive storyteller system, which can be used by primary school educators as a tool for storytelling. Although the level of popularity of a computer- aided instruction (CAI) in various skills such as readings , may vary. Few will dispute the facts that computers have won a permanent place in most classrooms. The most common concerns of educators now have to do with the appropriateness of many possible role computers can play in instruction. The emphasis however, should not be on computer to increase the achievement but rather on how the teacher uses computers meaningfully in instruction.

Plants in Production of Recombinant Antibodies

Plants in Production of Recombinant Antibodies Shirin Bagherihanaei A discussion of the techniques, advantages and disadvantages of the use of plants in production of recombinant antibodies for research and therapeutic use with named examples. Introduction   Ã‚   Application of plant for medical proposes goes back to thousand years ago. Our ancestors use plants and extract its beneficial substance to cure different illnesses and relief pain. This idea is continued with us and today we can manipulate the genetic information of plants to make them suitable for the production of recombinant protein and biopharmaceutical medicinal purposes [1]. Since the first generation of recombinant protein from tobacco cell culture, a variety of pharmaceutical products have been introduced such as vaccines, hormones, antibody, growth factors, and cytokines [1,4,9]. However, AB is the most common recombinant protein which is generated by plants and it has been called plantibody. Nowadays the development and the use of transgenic plants for production of recombinant ABs is an attractive subject among scientists because plants are easy to work with and also the cost of the production is considerably low. It is also beneficial because of the large-scale productio n [1]. Production of high quality recombinant protein for research and therapeutic purposes from mammalian are quite expensive, therefore the idea of producing recombinant protein in transgenic animals and plants has formed recently [1]. In this essay, I try to summarise and highlight some of the most cutting-edge techniques in the use of transgenic plants for production of recombinant protein and antibody. I also discuss their advantages and disadvantages with the utilization of plants to produce antibody. Plantibody Plantibody made up of two words: plant and antibody. It means plantibody is an AB that is generated from plants. Antibody is a glycoprotein which mainly made by plasma cells and used by the immune system to neutralize any kind of foreign molecules inside the body such as bacteria and virus. Plantibody has this property to recognize and bind to its specific antigen. It can be generated from tobacco, rice cells culture, Lemna minor (duckweed), Arabidopsis thaliana seeds, Medicago Sativa (alfalfa), lettuce and maize [2] but tobacco is the most common source due to its high leaf biomass yield [3]. According to a report, recombinant protein level in tobacco stem is the same as this level in its leaf. That means to produce recombinant therapeutic protein, the whole plant biomass can be used [3]. Another advantage of tobacco is that it is not edible and this aspect of tobacco reduce biosafety concern but it contains toxic alkaloid and the plant should be purified from the toxic chemicals [3]. As tobacco is not an edible source, regulatory issue for production of recombinant protein is less controversial than food crops such as rice, soy bean and corn. Chinese cabbage has the highest amount of soluble protein among plants. Production Techniques Production of the recombinant protein includes utilizing the whole plant or plant cell culture in vitro [9]. The disadvantages of using the whole plant for production of recombinant AB are: time-consuming generation of transgenic plants, the risk of contamination with fertiliser, unstable quality and yield of the products, applying good manufacturing practice (GMP) to the whole-plant production pipeline [9]. Plant cell suspension culture has the benefits of both mammalian cell culture and whole plants. Undifferentiated plant calli can be developed under a proper condition in the liquid media environment and produce cell suspension culture. Plant cell culture can generate proteins which are more similar to human generated proteins. They can also grow rapidly in a simple media same as bacteria. Plants are eukaryote so they have fairly similar post-transitional modifications such as glycosylation that happen in human cells [9]. Glycosylation is an enzymatic process that glycan adds to o rganic molecules such as lipids and proteins. Correct pattern of protein folding is also essential for recombinant protein to function [1]. It is interesting to note that plant suspension cell culture lack fully functional plasmodesmata, therefore, systemic post-transcriptional gene silencing (PTGS) may be reduced because PTGS is transmitted through plasmodesmata and the vascular system [9]. Generally, three different methods are applied in the production of recombinant AB in plants: Agroinfiltration with recombinant agrobacteria, particle bombardment technology and Infection with modified viral vector [8,14]. The general technique for the production of genetically modified plants is agrobacterium-mediated transformation [2]. Agrobacterium Tumefaciens is a gram negative bacteria which is the cause of crown gall disease in plants [14]. These bacteria live in soil and attract to the plants with wounded parts. However, scientists use this bacteria as a tool for research and therapeutic purposes by introducing the gene with desired properties into the plant cells in plant genetic engineering. The gene of interest can be inserted into Ti plasmid (tumor inducing) then injected into the plants as a host. Plant cell divide out of control and the gene of interest proliferate as well [14]. There is a selectable marker on the T-DNA which is transferred into the host cells therefore it is possible to control if the gene is transferred successfully or not [2]. There are two transformation strategies for generation of recombinant antibody, Stable and transient expression. Stable expression is the stably insertion of cDNA encoding both heavy and light chains of AB into the genome of plants. The gene can be introduced into the chloroplast genome to produce chloroplast transgenic plants which can generate AB with correct folding and disulfide bonds. Some example of the transient expression is agroinfiltration and recombinant plant viruses for the production of antibody [3]. Agroinfiltration system has been used to produce multi-antennary N-glycan that mostly seen in mammalian derived glycoproteins [3]. Transient expressionmethod is fast and convenient for the production of recombinant antibody without generation of transgenic plant. The generation of transient expression is the precondition to stable transformation because it can test expression vectors and protein stability and also it is able to recognize any problem that may have happened [ 8]. Transient expression is better for low scale yield protein production yet transgenic plant are better approach for high yield production and also gives a better expression levels [7]. An important point to note is if the expression is targeted to the endoplasmic reticulum (ER), this results in higher yield [7]. Another approach for the insertion the gene of interest into the plant tissue is particle bombardment technology. The main idea of this technique is some microscopic golden bullet or tungsten bullet covered by the gene of interest. These particles are fired into the plant leaf. This technique used for all type of plants. The golden bullet preferably used because the tungsten bullets have the risk of toxicity for the plants. Then the bullet is placed at the end of plastic bullets and shoot with blasts of air or helium. There is a plastic mesh work shop on the way of the bullets which guide the bullet to move forward. An alternative technique used for this approach which can accelerate the beads with strong electrical discharge which results in a controlled penetration of beads into the plant tissue. After penetration of the DNA dissolved into the cytoplasm of the leaf, the gene of interest can recombine with the chromosome of a plant. Finally, the leaf is transferred to media and let it grow and regenerated using tissue culture [8,11]. This technique does not use a lot due to its high cost and also as this method is physical so the insertion of the gene which is performed by gene gun may cause damage to plant without transferring the genetic material inside the plant and dose not give the precise or desirable results [14]. Production of ab transgenic plants can be generated by viral vectors. However low infectivity with this vectors needs to be considered as an obstacle [2]. One of the disadvantages of viral plant system is the injection of vector to leaf or stem every time which can result in gene mutation during replication of the virus. But we dont face this problem in transgenic stable expression. Therefore, it is extremely important to choose the proper protocol for gene ex pression [3]. Advantages and Disadvantages Plants paly an important role as a bioreactor for production of recombinant protein. Basically, the common systems use for the production of recombinant proteins is the manipulation of mammalian cells, bacterial systems, yeast and etc. However, recently due to some negative aspects of these systems many scientists prefer to work and study plant sources which have those benefits that they are looking for. There are several important benefits with the production of recombinant AB from plants. Firstly, is the large scale of production from cheap raw materials and the reduction of costs in comparison with other techniques of recombinant AB production such as yeast, mammalian and etc. [3,5]. Another advantage of using plants for production of AB is the flexibility of working with plants as it can be used both in vivo and in vitro [3]. In addition, introducing new transgenic plants is possible by sexual crosses and they are quite easy to work with. There is a very low risk of contamination by mammalian viruses when AB is generated from plants [5]. Another advantage is correct folding and assembly of produced AB for both single stranded peptides and multimeric protein with full size. Recombinant protein which generated from edible sources does not require purification. In terms of storage the enzymes which are produced by plants can be formulated to the seeds, so under the suitable condition they can be stored for long period of time and it is also possible to transport them to different locations easily. Plantibody have both avidity and affinity towards its specific antigen and its characteristics maintain the same after purification [1]. Although plants have lots of benefits but it is not 100% perfect source for production of antibody [3]. The most important disadvantage is the fact that Plant N-glycosylation is different from human and mammalian glycosylation. Another negative point is that plants has shown discrete yields due to low gene expression level [7]. There is also the problem with causing allergic and immunogenic reactions in humans, which is because of the difference in glycosylation pattern in humans and plant [7]. Moreover, there are some concerns regarding the activity of proteolytic degradation, which might influence fully assembled IgG that is secreted in the culture media [9]. Production of mycotoxin by impurities, limitation which caused by the environmental condition, and the possibilities of herbicides presence in the product are some other negative aspect of transgenic plants [1]. The controversy about plantibody generation is the presence of gene segments or marker segments in the produced drug and its effect on human body and the probability of allergic reaction to plant glycoprotein [1]. Although there are some disadvantages with the use of transgenic animals such as the risk of contamination of protein with animal viruses and also it takes a long time to produce recombinant protein from transgenic animals but, many biotechnologists prefer to produce AB from mammalian cell lines because the final ABs have a correct glycosylation pattern and protein folding [1]. Plant Antibody Application The extracted AB from plants can be used for many different purposes such as vaccine production, clinical diagnosis protein, pharmaceutical and industrial proteins, biopolymer, biodiesel, food industry, tools for research, and diagnosis tool for chromatography and other immunoassays [1]. The application of AB in research is extremely wide, because of their transferability with the metabolic process in organism [1]. Protein pharmaceutical products are one of the most expensive and important products that human has managed to synthesis them in ways other than natural methods. In recent years, mAB has had an important role in the diagnosis and treatment of cancer-related research [3,12]. Each mAB influence cancer cells in 3 ways: it can signal to the immune system to kill cancerous cells, it can prevent the division of cancer cells or deliver drug to these cells [3]. mAB can attack tumour cells by complement system in cytotoxic reactions through complement system. They bound to the tumor cells which prevent tumor growth and finally result in apoptosis [3]. The ability of AB to prevent the pathogens and tumor cells is due to the affinity of the variable binding sites. This affinity of AB could have enhanced by modifying glycon structure and glycosylation patterns [3]. As we see mAB have many positive aspects for prevention of cancer but their application is not common which is duo to the risk of contamination with human pathogens, high cost and proliferation inability. However, these problems have been eliminated by the production of mAB from other bio-organism like bacteria, yeasts, insects, and plants [3]. The monoclonal AB expressed in plants by tobacco mosaic viru s vectors [3]. Nimotozomab is a humanized anti-epidermal growth factor receptor recombinant AB which is produced in animal cell culture. This AB is used for treatment of different carcinoma cells. It seems that a mutation in the N297 position in the IgG1 FC region of this AB and apply it in a transgenic plant which result in producing a form of nomotozomab that is similar to mammalian-cell-produced AB. It also has the property to block the EGFR interaction and have antitumor effects [5,7]. Nicotiana tabacum were transformed by A.tumefaction-mediated gene transfer method. In order to infect the plant cells, recombinant pDEGF-R Agbacterium bearing the binary vector was applied [5,7]. According to experiments the mAB which was generated in plants was as effective as the one which was generated in mammalian (nude mice). In another experiment marine, mAB could prevent Brest cancer cell growth and mAB was generated from transgenic tobacco plant which had the same function as the murine mAB. Therefore, pl ants such as tobacco can produce two different mAB which can target two different types of cancer cells [3]. The most frequently chosen host cell lines used for recombinant protein expression are Tobacco BY-2 (Bright yellow-2) and NT-1 (Nicotiana tabacum-1) cells [9]. Generally, IgA, IgG and IgM are generated from plants. IgA and IgM have the potential for commercial production. They attach antigens in the first line defence at gastrointestinal mucosal surface, tears, saliva and milk [14]. IgG and IgA have been introduced in Nicotiana, Arabidopsis. Plantibody have a high level of safety which rise the interest for production of mAB from plant Examples include the Guys 13 IgG1 (Fischer et al., 1999b; Sharp and Doran, 2001a, 2001b), a human mAB against hepatitis B virus surface antigen (HBsAg) (Yano et al., 2004), a human anti-rabies virus mAB (Girard et al., 2006), and most recently a human anti-HIV mAB (Holland et al., 2010) all of which have been reported to be expressed in tobacco cell suspension cultures [9]. Lots of effort have been done for production of these ABs in large scale but none of them sell in the market due to the high cost. Nonetheless, two plantibody is used in clinical CAROX which was expressed in transgenic tobacco that takes part in the prevention of tooth decay and the second one have an effect against non-Hodgkin-lymphoma(NHL) [2]. The following table demonstrates some IgA plantibodies which are generated in recent research. Plantibody Source Target Plantibody Characteristic sIgA/G Transgenic Tobacco Plant S. Mutans Prevention of tooth decay Human IgA Maize Herpes Simplex Virus and saga 1 antigen Herpes disease and sperm agglutination Coccidia specific chicken IgA Nocotiana Benthamiana Eimeria Acervulina Against the coccidiosis Virus-specific IgA Tomato and Nocotiana Benthamiana Rota Virus Development for passive immunisation against Diarrhoeal disease Chimeric Enterotoxigenic Bacteria-Specific IgA (VHH-IgA) Arabidopsis Thaliana seeds Enterotoxigenic Escherichia Coli (ETEC) Passive Mucosal Immunisation Against Enteric Infections Chimeric Toxic-Specific IgA (Hybrid IgG/IgA) A. Thaliana Shiga Toxin From ETEC Against Haemorrhagic colitis and Hemolytic-uremic Syndrome Monomeric IgA1 K! Variants (Infliximab, Adalimumab, Ustekinumab) N. Benthamiana Against Autoimmune disease 2G12 sIgA N. Benthamiana Human Immunodeficiency Virus Anti-HIV Human This table shows IgA plantibodies, their sources, targets and characteristics. Conclusion and future perspectives Although there are problems with the generation of plantibody from mammalian cells, but they are the most common source for production of mABs. This is due to the correct folding and similar glycosylation patterns to human, complex type N-glycosyl, moieties and the presence of polypeptides with disulfide bonds. Using recombinant antibody fragment in research therapeutic purposes, biotechnology and pharmaceutical science is increasing because of the intrinsic properties of the components such as the ability to penetrate better and detect antigen with higher affinity, small size and easy production compared to AB full size [6,13]. More powerful tissue or inducible promoters, enhancement of transcript stability, translational improvement with cutting edge sequences or strategies and transgenic chloroplast system are some ways which are studied in order to raise the AB expression level in plants in the future [8]. Drug production seems to be one of the promising field in terms of commerc ial development in biotechnology [1]. In total, we can see a promising future for the production of drugs, vaccine, recombinant protein and biopharmaceuticals from plants. However, several bottlenecks including regulatory guidelines, ethical issues and public approval must be taken into account and solved [1]. References: Hashemzadeh, H. and Zebarjadi, A. (2014). Application of transgenic plants as factories for producing biopharmaceutical. [online] www.researchgate.net. Available at: https://www.researchgate.net/publication/268514150_Application_of_transgenic_plants_as_factories_for_producing_biopharmaceutical?enrichId=rgreq-4465fb2b3b0479dec4752b8195daab6c-XXXenrichSource=Y292ZXJQYWdlOzI2ODUxNDE1MDtBUzoxNjU2NDA4MDM0NjMxNjhAMTQxNjUwMzI1MzMxOA%3D%3Del=1_x_3_esc=publicationCoverPdf [Accessed 17 Mar. 2017]. Frenzel, A., Hust, M. and Schirrmann, T. (2013). Expression of Recombinant Antibodies. [online] journal.frontiersin.org. Available at: http://journal.frontiersin.org/article/10.3389/fimmu.2013.00217/full [Accessed 17 Mar. 2017]. Moussavou, G., Ko, K., Lee, J. and Choo, Y. (2015). Production of Monoclonal Antibodies in Plants for Cancer Immunotherapy. [online] Hindawi.com. Available at: https://www.hindawi.com/journals/bmri/2015/306164/ [Accessed 17 Mar. 2017]. Valdà ©s, R., Padilla, S., Gà ³mez, L. and Borroto, C. (2003). Large-scale purification of an antibody directed against hepatitis B surface antigen from transgenic tobacco plants. [online] www.researchgate.net. Available at: https://www.researchgate.net/publication/10635451_Large-scale_purification_of_an_antibody_directed_against_hepatitis_B_surface_antigen_from_transgenic_tobacco_plants?enrichId=rgreq-9f9d9c1d7e1ac5013b459ed8c8d81938-XXXenrichSource=Y292ZXJQYWdlOzEwNjM1NDUxO0FTOjk4OTYxOTIyNzIzODQ1QDE0MDA2MDU3NjkyNjc%3Del=1_x_3_esc=publicationCoverPdf [Accessed 17 Mar. 2017]. Pujol, M. and Gavilondo, J. (2013). Transgenic plants of Nicotiana tabacum L. express aglycosylated monoclonal antibody with antitumor activity. [online] www.researchgate.net. Available at: https://www.researchgate.net/publication/263802548_Transgenic_plants_of_Nicotiana_tabacum_L_express_aglycosylated_monoclonal_antibody_with_antitumor_activity?enrichId=rgreq-e820e9544359d3a71edb5ce55845f43a-XXXenrichSource=Y292ZXJQYWdlOzI2MzgwMjU0ODtBUzoxMTczNzkwNTI4NzE2ODFAMTQwNDk5Njc1NTQwMg%3D%3Del=1_x_3_esc=publicationCoverPdf [Accessed 17 Mar. 2017]. Hayes C. Generation and Application of Recombinant Antibody Fragments for Prostate Cancer Detection. A thesis submitted for the degree of Ph.D. School of Biotechnology, Dublin City University,Dublin 9,Ireland 2010 j6) Rodrà ­guez, M., Pà ©rez, L., Gavilondo, J., Garrido, G., Bequet-Romero, M., Hernà ¡ndez, I., Huerta, V., Cabrera, G., Pà ©rez, M., Ramos, O., Leyva, R., Leà ³n, M., Ramos, P., Triguero, A., Hernà ¡ndez, A., Sà ¡nchez, B., Ayala, M., Soto, J., Gonzà ¡lez, E., Mendoza, O., Tiel, K. and Pujol, M. (2012). Comparative in vitro and experimental in vivo studies of the anti-epidermal growth factor receptor antibody nimotuzumab and its aglycosylated form produced in transgenic tobacco plants. [online] http://onlinelibrary.wiley.com. Available at: http://onlinelibrary.wiley.com/doi/10.1111/pbi.12006/full [Accessed 17 Mar. 2017]. Yu-Cai Liao , He Pingli , Chun Senzhao , Ming-Jing Yao , Jing-à ¢Ã¢â€š ¬Ã‚ ¨Bo Zhang Jin-Long Liu (2006) Plantibodies: A Novel Strategy to Create Pathogen- Resistant Plants, Biotechnology and Genetic Engineering Reviews, 23:1, 253-272, DOI: 10.1080/02648725.2006.10648087. Xu, J., Ge, X. and C. Dolan, M. (2011). Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures. [online] Sciencedirect.com. Available at: http://www.sciencedirect.com/science/article/pii/S0734975011000036 [Accessed 17 Mar. 2017]. Innovateus.net. (n.d.). What is DNA Particle Bombardment?. [online] Available at: http://www.innovateus.net/science/what-dna-particle-bombardment [Accessed 17 Mar. 2017]. Clark, D. and Pazdernik, N. (2009). Biotechnology. 1st ed. Beijing: Ke xue chu ban she, p.405. 1.Adams GP, Weiner LM. Monoclonal antibody therapy of cancer. Nat Biotechnol 2005 Sep;23(9):1147-57. 2.Souriau C, Hudson PJ. Recombinant antibodies for cancer diagnosis and therapy. Expert Opin on Biolog Ther 2003 Apr;3(2):305-18. Hayes C. Generation and Application of Recombinant Antibody Fragments for Prostate Cancer Detection. A thesis submitted for the degree of Ph.D. School of Biotechnology, Dublin City University, Dublin 9, Ireland 2010. Gà ³mez, L., Valdà ©s, R., Pujol, M. and Brito, J. (2011). Kinetic of Expression of a Plantibody in (Nicotiana tabacum) Plants Cultivated in Different Substrates (Zeolite and Soil). [online] www.researchgate.net. Available at: https://www.researchgate.net/publication/287551483_Kinetic_of_Expression_of_a_Plantibody_in_Nicotiana_tabacum_Plants_Cultivated_in_Different_Substrates_Zeolite_and_Soil [Accessed 17 Mar. 2017]. Vasilev, N. (2015). Developments in the production of mucosal antibodies in plants. [online] Sciencedirect.com. Available at: http://www.sciencedirect.com/science/article/pii/S0734975015300525 [Accessed 17 Mar. 2017].

Y2K Bug :: essays research papers

Y2K – The Big Issue Abstract and Executive Overview What is the Y2K issue? This paper will describe the problems associated with Y2K and how Industry, Government, and Small Businesses are handling the problem. The first chapter introduces the Y2K issues. Chapter 2 will define how this affects the different businesses and Government agencies. Chapter 3 will develop an overall plan on how to attack the problem and recommendations. The majority of this paper will develop a plan on how each of the businesses and Government agencies should attack the Y2K problems. There should be a logical approach to planning how to investigate, test, validate, and if required, develop a contingency plan for Y2K. The job is to either form a team of personnel or hire a consulting firm to assess your situation. The team should employ the following steps: assess the system, renovate the system if necessary, validate the renovation if necessary, implement the renovation if necessary, test the renovation if necessary, and finally have a contingency plan in the event that renovating the system is not feasible and/or is too late. The only necessary or required action is to assess the system. This will be discussed in detail in my paper. The real issue is that less than a year remains before the year 2000 problems are here. The recommendation is to begin working this issue now. It may be too late, but that is when the contingency plan comes in handy. TABLE OF CONTENTS 1. What are the Y2K Issues? 2. What impacts are they’re to Government, Industry, and Small Business? 3. What can Government, Industry, and Small Business Do to Combat the Y2K Issues? 4. Recommendation 5. References 6. Glossary Chapter 1 What are the Y2K Issues? There are actually more dates than just the year 2000 date. There are dates that can impact the leap year algorithms; Julian dates, fiscal year dates, calendar dates, and ASCII code dates. The top dates that need to be checked are: 1. 9 September 1999. This date can be read in code as 9999. In computer language, specifically ASCII code, this translates into a request for the processor to stop processing. 2. 1 October 1999. This is the start of the new Fiscal year for the Government (FY00). The algorithm for this may not be able to go from FY99 to FY00. 3. 31 December 1999.

The Bachelor: Expectations For Love Essay -- reality TV, culture

What does the show, "The Bachelor", say about our expectations for love in our culture? The search for love is a dilemma most people are faced with at some point. Many different reality shows have been released over the years focusing on relationships. However the television show, The Bachelor, takes reality T.V. dating to the next level. Different from most dating reality T.V. shows, the participants on The Bachelor are looking for much more than just a relationship; the end goal is a proposal. The show revolves around a single bachelor who is essentially dating an entire group of woman, typically starting the first episode with around 25. As the show advances the bachelor eliminates women by not offering them a rose during the ceremony. All of the women that do receive a rose are invited to stay another week at the house while continuing to go on dates with the same man. Early in the season, the bachelor goes on large group dates with all of women at once but as the season progresses; the remaining women are also invited on one-on-one dates. The problem with this sh ow is that it depicts love in an illogical way. Because she is the last woman, the bachelor’s logic dictates that she must be the right woman for him. The women and the bachelor of the show are whisked away to romantic and tropical areas to live while dating each other. Aside from the fact that the man these women are dating also is dating 24 other women, the participants in this show are completely removed from actual reality. There is no strain or issues that they have to work through like the real world with honest relationships. In this paper I will explain the issues with The Bachelor and what affects it has on our culture. My research question is: What does... ... together. Just because a person feels passionate love does not mean it leads to companionate love. The Bachelor leads our culture to believe that simply by longing to be with someone means you are in love. If our culture continues to attempt to keep up with the definition of love according to The Bachelor then real love, companionate love, might fade out all together. Works Cited Mickel, E., & Hall, C. (2008). Choosing to Love: The Essentials of Loving (Presents and Problems). International journal of reality therapy, 27(2), 30-34. Kito, M. (2005). Self-Disclosure In Romantic Relationships And Friendships Among American And Japanese College Students. The Journal of Social Psychology, 145(2), 127-140. Sassler, S, F Addo, and D Lichter. "The Tempo of Sexual Activity and Later Relationship Quality." Journal of Marriage & Family 74.4 (2012): 708-725.

Leadership in Braveheart Essay -- Leader Leading Braveheart Essays

Leadership in "Braveheart" In today's rapidly changing world, leadership is necessary to keep up with the competition. In the extract from the film â€Å"Braveheart†, William Wallace demonstrated many leadership techniques that helped his army prevail as an underdog. Many of the techniques Wallace used are prevalent in modern day business leaders as well. By stepping up in a leadership role, Wallace gained the respect of the entire army even though he was not the man that was put in charge. One of the main things that Wallace did was lead through his actions. By stepping up to the front line, it showed his troops that he was not scared and this attitude was imitated by the rest of the troops. In the present day business world, an effective leader hears what others have to say and helps them with their issues. This is just what Wallace did. In the short extract of â€Å"Braveheart† Wallace showed what was necessary to be a successful leader. There are many lessons that should be gained from watching William Wallace. First, no matter what the situation was, he was very calm and composed. He was very calm when speaking with the head of the opposing army and very composed while his army was being charged at by opposing forces, even though they were obviously much outnumbered. Another characteristic of how Wallace displayed leadership was his confidence and sense of humor throughout the entire scene. He ordered his troops to pull their pants down and â€Å"moon† the English in the middle of a war standoff. I think that this was a very good technique to loosen up the troops and make them more comfortable and confident. Also his confidence was very apparent throughout the war. He told his army that they would lose some lives but in the end they would recover their freedom. The army saw his confidence and in turn , they became more confident about victory as well. Other techniques Wallace used were being inspirational, motivational and patriotic. Before the war started, most of the troops were very uneasy and started to turn around and head home. Wallace came to the front of them, got their attention and made a very inspiring speech that fired them up and turned there attention back to the task at hand. The Scottish army was ready to turn back and concede their freedom to the English. Wallace showed patriotism by painting his face blue for the Scottish flag and encouraged h... ...man and the maker of the Model T Ford car. He said, â€Å"If money is your hope for independence you will never have it. The only real security that a man will have in this world is a reserve of knowledge, experience, and ability.† William Wallace was never interested in money or fame. He stood up for what he thought was the right thing, and encouraged his followers to do the same. â€Å"Failure is the opportunity to begin again, more intelligently†, says Ford. Ford knew that he would not succeed at all times but if he learned from his mistakes and tried again, he would eventually win. Wallace had the same mentality. He knew that his army would lose some of their troops during the battle, but if they were victorious, they would learn from there loses and grow strong again. There are many leadership lessons that William Wallace exposed in this short extract of â€Å"Braveheart†. These examples of leadership are very important in being a successful leader in the modern day business world as well. By standing strong in adversity, Wallace got the attention of his army and inspired them into battle. Wallace acts as a great guide of how businessmen should effectively lead their employees today.

Emergency Preparedness and Disaster Response in Schools Essay

The professional nurse uses clinical judgment and decision making skills to provide appropriate nursing care and collaborates with other health care professionals responding to the emergency or disaster. The purpose of this paper is to outline the professional nurse’s role and how the nurse works with other responding personnel as well as the community affected in the event of a tornado that affects a school. The Role of the Nurse A disaster is defined as any natural or human-made incident that causes disruption, destruction, and/or devastation requiring external assistance (Stanhope, 2012). Schools are generally considered a safe haven for the children attending, but various types of emergencies can occur within the school walls that impact the school and the surrounding community. Severe weather can be a natural disaster when it produces tornadoes. Tornadoes have proven to be large scale disasters, causing problems ranging from loss of power to major structural damage and resulting in physical injuries, including loss of life. Tornadoes outside of a school setting cause severe damage and casualties, but when the tornado hits a school it becomes a disaster setting for all school personnel and the school nurse. The school nurse immediately is looked at when there is any type of medical emergency. When there is an entire school that has been affected by destruction like a tornado, the school nurse is most definitely overwhelmed with patients. The nurse must be prepared and work closely with all responding personnel to ensure a timely response to all affected, inside the school and the parents affected outside the school. The school nurse is an expert in the nursing process and should utilize these steps in order to care for all involved in a disaster like this. The professional nurse, through her education, should be prepared to utilize the nursing process (assess, plan, implement, evaluate). It is critical the school nurse knows his/her role prior to the disaster. His/her role includes triage, coordination of the first aid response team, and direct hands-on care to the victims of the emergency. The school nurse also plays an important role in the mental health support for the students and faculty involved during the emergency and in the recovery phase of the emergency. The nurse must be able to identify with and be able to communicate with all responding healthcare personnel. The responding will include, but is not limited to, firefighters, both paid and volunteer, EMS personnel, Emergency Management Personnel, law enforcement, and local healthcare providers, such as physicians and nurses. The school board office will also have responding personnel to the scene as well. The main goal of the professional nurse is to communicate with all responding personnel and ensure that everyone involved in the response clearly knows their role and who they should report to. Nursing Strategies Every community can always improve in their response to emergencies and disasters. Planning before the disaster hits is the key. Preparations for a facility’s response to an emergency involving realistic training exercises, (O’Boye, 2006) can greatly reduce anxiety levels and increase the likelihood of more positive results. Some examples of emergency and disaster planning includes, but is not limited to, mock exercises, more interagency cooperation in the mock exercises, identifying how we, as a community, will respond, who would be in charge of communications, who would be in charge of logistics, and a list of every one’s role in the emergency response (Laureate, 2012). The school nurse is in a leadership position to provide continuous coordination and training of all school personnel as well as the communities involved as part of the school’s emergency plan. Implementing the National Incident Command system into the school’s emergency plan is vital. This system includes universal protocols and language (Stanhope, 2012). This system acknowledges the need for mutual aid response and allows for easy to understand communication and description of roles no matter what agency or community the responders come from. This system should be implemented in every school because when a disaster strikes, especially at a school, people come from all over the country to render aid and this system provides a framework that everyone can understand. Summary The school nurse’s assistance in community-wide planning groups is helpful in the facilitation of a rapid, coordinated, effective emergency response within the framework of the Incident Command System. This includes establishing standard emergency response plans and participating in skills, drills and exercises to evaluate the response capabilities of a school, as well as the effectiveness of the plan (NASN, 2013). Disasters occurring at schools create a larger scale disaster because not only is there the disaster inside the school, but there is also a disaster created outside the school from all of the parents wanting answers that sometimes takes hours to produce the answers to. Planning is the key and the school nurse is in the position to help in the planning of the response plan in these disasters.

Paul Cezanne, Pines And Rocks Essay

Paul Cezanne, Pines and Rocks, 1896-99 Oil on Canvas Museum of Modern Art This simple painting of a small, intimate landscape is a good example of Paul Cezanne’s mastery of the impressionist style. The scene is of a rocky path, possibly a hiking trail on the side of a mountain, and a few trees that veil the sky in patches of leaves. Cezanne’s method of painting is rather interesting, in that he paints each stroke like a plate of color, creating an overlapping mosaic. The palette he chose is also remarkable with bright, almost cartoonish shades of pigment that give an underlying sense of realism to the painting. Looking at Cezanne’s work often makes one wonder if impressionism is a study of light being cast on objects or of life being cast out from the object. The overall â€Å"feel† of a painting is often determined by the way each brushstroke is applied to the canvas. Cezanne’s work resembles a mosaic piece, except his blocks of color are intermixed and overlap eachother. Each brushstroke rests on its own plane in the painted space, giving the painting a sense of depth unique to the three-dimensional information of the trees off in the distance and the boulders on the ground. The thick, dark outline of the trees and rocks also add depth to the piece, separating the shaded trail from the bright midday sky. Using a little imagination, one can almost pick off individual leaves from the green and brown patches of paint used to represent them. Cezanne’s choice of color is exceptional in expressing the particular mood in a scene, as shown in this painting. A rich blend of purples, reds, and browns in the rocks and tree trunks nicely compliments the bright blue sky and green foliage. The dull, muted tones of the rocks give weight and gravity to the scene while the light and dark greens seem to dance in the winds of the sky blue background. Lighting and shadows are also well done to add the final touch of depth to the piece.

Opening a Daycare Essay

One of the most important demands of the early years, care and education that offer young children a quality care and education to operate effectively. Early childhood education has become formalized in its processes and entrepreneurial in mode, particularly in the urban and middle-class centers. Centers for pre-school children are necessary particularly because the entrance of more women into the workforce creates a need for places where their children can be safe and given some education while the parents are at work. However, these centers should ot be made an excuse for parents to abdicate their responsibility for child care and nurturance, and for making early childhood education a commercial activity. Children with special needs may require individual learning programmed for a part of the session in center. A Child Day care center, group child care home and family child day care home and group child day care home are center for children. For these reasons, it is proposed that early childhood centers be organized community or neighborhood centers to be staffed by a minimum number of professional arly childhood educators with maximum help from parents who should take turns serving these community or neighborhood daycare centers. In opening a daycare center it needs the quality care and education that should be available to all children if their parents wish it. To deliver a high quality service and the the important that all reflect on their practice so that they can acknowledge how things have gone and whether there is room for improvement. A good starting point is to examine the principles which is part of the early years, Care and education. The welfare of the child ( the children must come first) in managing children’s challenging behavior. The child care and education should emphasize the positive aspects of behavior and physical punishment must never be used. Children’s learning and development (children need activities) which will stimulate their social, physical, intellectual, emotional, and moral development by careful observation of the child. Keeping children safe to ensure that the setting is safe for the children and the prevention of accidents and the protection of health. Planning is basically determining development goals, policies and plans; and setting, procedures and strategies needed to achieve the purposes. In the preparation of the plans, social economic and development administration programs are formulated separately within the context of policies. It deals with goals, setting process, environment, role, and budgeting. On another viewpoint, is seen on decision-making, information and the future. The process by which the guiding members envision its future and develop the necessary procedures and operations to achieve that future. In terms of identifying riorities and interests the important factor to achieve is the operational, efficiency and effectiveness in the delivery of the service ( the needs of the community). As we plan, the level of minimum standard must be observed to guarantee a Certain level such as facilities, staff, curricular content, utilization of space and time, procedures and financing schemes. These standards can be achieved through the conduct of survey, studies, operations research and cost-benefit and cost-effectiveness analyses. Steps in planning like goal-setting, information, policy, programs, implementation nd evaluation but the development planning consist of situational analysis, goal/objective/target setting, policy/strategy formulation, program/project identification, investment program, budgeting, implementation and monitoring evaluation and plan update. The situational analysis requires the conduct of survey and research studies. Gathering of demographic, economic, physical and others. A survey of undertaken Indicating past and present performances, programs and projects, manpower, budget and buildings, facilities and equipment. After that setting of goals, objectives and targets. A goal is a broad statement of an image of the future that seeks to achieve. And objective, the expectation which is pursued to satisfy the goal target, flowing out of the objective is the most specific statement of purpose which is measurable and achievable. Once the broad goals, objectives and target are framed, more specific policy statements and strategies are formulated for each area of concern as to social, economic and development administration aspects. The plan is basically a guide for any future decisions affecting the growth and development of the center. The Vision is the act of power of seeing an ideal state through mental acuity or foresight that a man or institution intends to accomplish (Kaufman et al. ,2002). It should be conceptually ideal, unitarily and purposively focused, and foremost should be intellectually challenging and exciting. The vision spells out in broad terms the role of the center. To specify what it intends to do and become considering the social, cultural, economic factors in the community. In vision we shared beliefs and values, impact from the environment, and attainment from future time. The Mission is a statement of philosophy of purpose for which it is created (Kaufman et al. , 2002). And goal as a desirable future condition which strives to achieve. It is normally broad in scope and long-term in its perspective. A goal dovetails the vision and mission of the organization or institution. To formulate the goals remember the clear statement about what the customer or client needs, who are the clients, and how plans to go about. The Objective is a specific description of an end result to achieve. It is a Translation of the broad goal into a set of more specific and concrete objective. The Translation of the goals into program objectives in terms of program offerings, research Services, extension and continuing education services, development services, income generation, capital outlay, and general administration. The Target is a more specific expression in quantifiable and measurable terms of what is intended to be accomplished. The specific end result, a target date and period; and the individual responsible and accountable in the accomplishment of the activity. The Policy and Strategy Formulation is a planning process about the rules and Decisions have been arrived to meet the goals and objectives. A policy is a purposive course of action or decision which is commonly set and perceived to be socially desirable to the great number of people. While strategy is the method or approach undertaken to accomplish goals, objectives and targets. The Program and Project Identification refers to the functions and activities Necessary for the performance of a major purpose for which it is established and Covering the activities that result in the accomplishment. Like support service, manpower training, curriculum development, extracurricular activities, production materials, eaching aids, technologies, improvement of the building and equipment. The Investment Programming is a phase in the planning process that resolves the activities need to be done with the greatest result. Formulated goals, objectives, targets and strategies in the development plan are translated into concrete, specific and implementable programs and projects packaged into the development investment program. Investment programming is the process of rational listing of programs and projects planned to be undertaken within a given time frame for the purpose of enhancing he process of asset and capital accumulation for some anticipated future benefits. This entails a systematic identification, preparation, selection , scheduling or phasing of programs and project given conditions of resource scarcity. The investment program serves as the basis for programs and projects that are considered in the preparation of the annual action plan and corresponding budget estimates. The Budgeting, this phase of the planning process resolves the money and fund available or allowable for the program, project or activity. Budgeting is one of the universal human experiences. All of us are faced with the problem of reconciling what we want with what we can afford. Every organization or institution must face the problem of balancing needs and desires. But the greatest problem arises when the resources are limited but needs and aspiration are sharply rising. Proper budgeting is important. The Implementation, this phase of the planning process how the plan executed, who are the responsible, how to determine the plan. It is an act of carrying out the plans, Programs and projects in accordance with the strategic plan in order to attain the set goals and objectives. The implementation of the plan in terms of stated policies, goals, objectives and targets translated into tangible programs, projects and services has to precisely specify as to who does what in terms of accountable and responsible with particular program and projects. On this regard, the owner or the president has to emphasize plan priorities in terms of benefits, materials, references facilities, equipment and others. The same principles should underpin early childhood education, in whatever setting (state, private or voluntary sectors). They are recognize with knowledge and skills hey have been learning from birth; quality care and quality education are inseparable; every child develops at its own pace; the role of the adult is to stimulate and encourage learning, trust, motivation and positive attitudes are important-each child should feel valued and secure; learn best through play, talk and first hand experiences; parents and teacher should work together in the best interest of the child. The early years of curriculum should be carefully structured to provide a balance of appropriate activities- some planned by adults others child planned or initiated; quality care and education equires well-trained educators and ongoing professional trainings skilled and careful observations are crucial to fostering children’s care and learning. (adapted from DfEE 2000). Licensing Standards of Daycare Centers should consider the following: The Activity Area available used by all children, Attendance of the actual present in the Center, Capacity of total number of children allowed in the center, Caregiver who provide care, supervision and guidance, Certification issued by CCD(Child Care Division), Child Care Facility, Comparable Group Care Program, Constracted Services; The Director who designated by the operator or administrator of the center, guidance and Discipline; Head Teacher, Staff, Operator, Owner, Parents, Program, Sanitizing, and others. The General Requirements for opening a Day Care Center are Certificate of compliance or certificate of registration, Application, Training requirements, Staff requirements, Director, Group Supervisor, Aide, Staff child ratio, Staff persons, Physical site, Program requirements, individual assessment and program, Caring and qualified staff, safe, clean facility, established rules and policy, and Complete schedule of activities. In opening a Day care Center it should be careful through out and need a research process. In daycare children help grow and develop their skills while also having fun. Good centers have a mix of activities that will teach different skills, projects that lead to Creativity, storytelling, dancing and singing and help the child learn instead of just Playing all day. Children also get to socialize with other children which they would not to Do as often if they were at home with a nanny. Finally, the centers are more stable and consistent than nannies because the center will watch your child even if a teacher is sick.